Glossary of Ingredients


DNA Repair Enzymes

DNA repair enzymes that recognize and correct physical damage in DNA, caused by exposure to radiation, UV light or reactive oxygen species. The correction of DNA damage alleviates loss of genetic information, generation of double-strand breaks and DNA crosslinkages. 

Having used DNA repair enzymes in Heliocare products for 20 years, studies have proven the efficacy of glycosylase in photoprotection and endonucleases for repairing DNA damage.


Fernblock® is the base active ingredient of all Heliocare products. It is an exclusive standardized extract of Polypodium leucotomos with powerful protective, antioxidant and restorative action that works both topically and orally. Its active ingredients act on all four types of radiation (UVB, UVA, Visible and IR) and prevent both their immediate damage (burns) and those that arise over time: skin aging, dark spots, loss of defenses, allergies & skin cancers.

Fernblock has shown numerous benefits in more than 50 studies and scientific publications. The effectiveness of this technology continues to be investigated with excellent results.


New Polypodium leucotomos extract with higher concentrations of the main polyphenols responsible for its antioxidant and photoprotection activity. Its photoprotection, DNA protection and repair, and anti-aging properties are significantly greater than those of Fernblock®.

Fernblock®+ demonstrates greater photoprotection activity in vivo: oral administration produces twice as great an increase in MED as Fernblock®.

Fernblock®+ produces a 2.4 times greater reduction in CPD formation (sign of DNA damage) in fobroblasts upon UVB irradiation vs Fernblock®.

One of the negative effects of sun exposure is hyperpigmentation of matrix metalloproteinases (MMP), responsible for collagen degradation and thus skin aging. Fernblock®+ reduces MMPs induced by both visible light and IR to a greater degree than Fernblock®.

Fractional Biomimetic Melanin

Heliocare 360° is equipped with fractional biomimetic melanin technology and contains plant tyrosine and amino acid that absorbs visible light 400-500nm. Fractional biomimetic melanin has double the absorption compared to regular melanin and works safely on the epidermis while not being absorbed into the blood stream.

Green Tea

Research has established that topical application of green tea leaves or extracts have many benefits for the skin, including anti-aging properties. The polyphenols in green tea possesses potent antioxidant and skin soothing properties and show significant promise for improving the appearance of sun-damaged skin.


Lycopene is a plant nutrient that gives read and pink fruit their colour. It boasts antioxidant and anti-inflammatory properties and has been extensively researched over the past 70 years.


Lutein is a carotenoid with antiinflammatory properties and is used by Heliocare with the purpose of helping to protect the macula from free radicals.

N-Acetyl Cysteine (NAC)

Stimulates synthesis of Glutation (GSH), a major endogenous antioxidant produced by cells:

 - participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintaining exogenous antioxidants such as vitamins C and E in their reduced (active)state.

 - used in metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport and enzyme activation.

NAC maintains fibroblast survival after UVA radiation and protects against oxidative and UV-visible light photodamage. 


Also called Nicotinamide, is a form of vitamin B3. It is necessary for cell energy metabolism and DNA repair.

It has powerful antioxidant activity, protects against cellular apoptosis induced by UVB in keratinocytes and maintains genome stability in presence of environmental stress factors such as sun exposure, pollution etc. It prevents and repairs photodamage to DNA (CPD & 8oxo Dg) and can also treat inflammatory skin conditions.


Also known as Oxothiazolidine, promotes cell metabolism and collagenesis. It is an important antioxidant that deters damage by reactive oxygen species and protects the epidermis, dermis and dermal-epidermal junction. 

The safety of OTZ-10 is shown in various studies with no cause of skin irritation, sensitivity, phototoxicity or photo-allergy. OTZ directly inhibits MMP-1 expression and shows potent antioxidant and detoxifying actions.


Vegetal active extracted from Physalis angulata, plant found in tropical regions where the sunlight incidence is more intense. 

Protects skin against infrared rays and visible light responsible for skin temperature increase leading to thermal aging.

 - Reduces collagen degradation

 - Reduces the interleukin action under inflammatory stress

 - Activates SOD and CAT enzymes

 - Maintains constant skin temperature even after long sun exposition

Polypodium leucotomos

It is a tropical fern native to Central America that in its transition from aquatic to terrestrial life developed mechanisms of self-defense and repair against the sun. The Chorotegas tribe of Honduras was the first to discover its excellent skincare properties. 

Cantabria Labs together with the research team of Dr Fitzpatrick of Harvard University (Harvard Medical School) demonstrated that this extract not only prevents immediate damage such as sunburn, but also provides protection capable of preventing long term negative effects such as DNA damage, skin aging, loss of defences or sun allergies.

Their extraction method is what guarantees maximum efficacy and safety: It is obtained from selected plants that grow under controlled conditions in laboratory processes according to Pharmaceutical Quality Standards.

Pomegranate Extract

When consumed orally, pomegranate helps the body defend itself against things that can lead to health concerns while minimizing oxidative damage via its nutrient profile, largely driven by antioxidant ellagic acid.


Non-digestable fiber compounds that stimulate the growth & activity of beneficial bacteria, especially bifidobacteria and lactic acid bacteria, in the gastro-intestinal tract, improving digestion and the effectiveness and intrinsic strength of the immune system.

Heliocare 360° contains Fibruline and Bioecolians to improve the skin's resistance by strengthening the body's immune defenses and to protect against skin damage caused by UV radiation, increase moisture levels and help prevent photoaging.

Vitamin C

Ongoing use has been shown to improve the look of multiple signs of aging, brighten an uneven skin tone as well as provide skin restoration and soothing benefits. It's also used to enhance the benefits of other ingredients in Heliocare products.

Vitamin D

Heliocare has added 100% of the RDA of vitamin D to the Ultra-D capsules so everybody can protect themselves without having to worry about their vitamin D levels. 

Beneficial to those with sun-related alterations, light phototypes, or patients with vitamin D deficiencies (elderly, diet, psoriasis...)

Vitamin E

One of the most well-known and researched antioxidants for the body and the skin. Vitamin E occurs naturally in human skin however can become depleted due to constant environmental exposure in the absence of sun protection.

Vitamin E is considered an anti-inflammatory agent in the skin and studies have supported its prevention of inflammatory damage after UV exposure.